baby put pill in mouth but didn't swallow
Camphor has been used with variable success for centuries for a wide variety of supposedly therapeutic effects.14 It is currently used by the public as a rubefacient, a chest cold inhalant, and a topical anesthetic. Benzocaine. Clin Toxicol 1995;33:223-231. A difficult pill to swallow: An investigation of the factors associated with medication swallowing difficulties. 72. Cardiac effects may occur with widening of the QRS and the Q-Tc interval. Gastroenterol Hepatol (N Y). Arch Dis Child 1979;54:22-225. Chlorpromazine (Thorazine) is a member of the aliphatic class of phenothiazines. See the specific topic that covers your child's main symptom for other treatment options. Pediatr Emerg Care 1998; 14:224-226. Place the smallest candy sprinkle on the middle of the tongue, Keep the head level (dont tip the head back), Have another sip of water to keep the pill moving. Kruse, JA, Carlson, RW. 103. Sudden, unexplained illness in your child could be a sign of accidental poisoning. Sertraline Intoxication in a Child. The GI manifestations, when severe, can include hematemesis. Which house or garden plants aren't safe around a baby? Ask about the possibility of a liquid or chewable form of the medicine. Gilman CS, Veser FH, Randall, D. Methemoglobinemia From a Topical Oral Anesthetic. Br J Clin Pharmacol 1983;15:502-503. Small Doses, Big Problems: A selected review of highly toxic common medications. Benzodiazepines and barbiturates are mandatory to treat brief seizures. This ensures that he ends the practice session with success. 78. 68. 26. 15. It may be unpleasant, but coughing actually helps dislodge the pill. The medical term for difficulty with swallowing is dysphagia. The original case report of pediatric fatality from oral acetonitrile ingestion was reported in 1988.19 Other fatal intoxications as a result of hydrogen cyanide overdose have been subsequently reported.20 The median oral lethal dose for children is not known. The Poison Child: Evolving Concepts in Care. Vet Hum Toxicol 1988;30:132-134. Golubluff N. Methemoglobinemia Due to Benzocaine. Avner ED. Freeman L, Wolford RW. N Engl J Med 1960;263:454-455. Most children present with effects by 2-4 hours post-ingestion.73 Atropinism can be the presenting constellation (dry mouth, difficulty swallowing, blurred vision, tachycardia, flushed skin, urgency, abdominal distention). Its important to stay calm if it happens. 112. In large doses, fluoride may act directly on the central nervous system, producing abnormalities such as visual disturbance, paresthesia, headache, optic neuritis, and seizures. If you are trying to take a pill and just can't seem to get it to go down, try using a piece of bread. This device gives the most accurate dosing. Tilt their head back only a bit (too far back, and it's harder to swallow). Double Gaps Metabolic Acidosis in Bilateral Basal Ganglion Lesions in Methanol Intoxication. Treatment of Severe Imipramine Poisoning Complicated by a Negative History of Drug Ingestion. Start with small pieces of candy or ice and progress to M&M's. Probably the most well-known method for swallowing a pill is to take it with water. He is refusing (crying) and won't try to swallow. Madsy S, Wax P, Wang D, et al. A volatile metabolite, dimethylselenide creates a garlic-breath odor. You have reached your article limit for the month. Desipramine is a congener and major metabolite of imipramine. Prescription Liquid Medicine and Your Child Refuses to Take It, Non-Prescription Liquid Medicine and Your Child Refuses to Take It, Techniques for Giving Liquid Medicine to Cooperative Child. Ann Intern Med 1996;124:726-728. Symptomatic patients should be admitted to an intensive care facility and treated with intravenous sodium thiosulfate. Our goal is accessible, continuous, comprehensive and coordinated care. These ingestions must be identified quickly and appropriate therapy promptly administered. Pediatrics 1992;89:999-1005. Aks et al reported vomiting, lethargy, respiratory depression, and seizures in three toddlers who ingested from 1 to 3 tsp of lotion.93. If a pill is stuck in your throat, you'll probably start coughing. Kloss JL, Boeckman CR. Cardiovascular compromise with pulmonary edema may require sodium and fluid removal through dialysis or hemofiltration.121. Lomotil Poisoning. Anderson IB, Mullen WI, Meeker JE, et al. 130. Also, use other positive rewards (treat, special DVD or stickers). Try to use substances that will melt quickly if they get stuck. Instruction on our part may contribute more to the future health of the child than any other strategy.131 We should not ever underestimate the influence of our secondary preventative efforts.132. Superwarfarin Poisoning in Children:A Prospective Study. Adverse effects from hyoscyamine sulfate overdose may be seen promptly after ingestion. J Pediatr 1993;122:982-984. You can also aim for the pouch inside the cheek. Caution: Swallowing cannot occur if the head is bent backward. Treatment of Severe Chloroquine Poisoning. Swallow the water and the pill. The public has long used quinine as an abortifacient.116. Put the pill under the tongue and take big gulps of water. J Emer Med 1993;11:415-425. 76. Perception of Toxicity and Dose by 3 and 4-Year-Old Children. Vet Hum Toxicol 1993;35:338. Cinchonism: Two Case Reports and Review of Acute Quinine Toxicity and Treatment. Vet Hum Toxicol 1991;33:354. Mix the dose of medicine with a strong-sweet flavor. Learn more. Am J Emerg Med 1998;16:443-497. When your child has mastered swallowing the first size, move on to the next size and so on. A large number of immediate-acting and sustained-released preparations have been marketed. Following acute ingestion, a minimum fatal dose for children is estimated to be 20 mg/kg.13,45 A 10 kg toddler who consumes a single tablet is at theoretical risk for a morbid outcome. If these conditions aren't treated properly, the lining of the esophaguscould be damaged. Central nervous system depression with coma can be compounded by drug-induced hypoglycemia. If he struggles, go back to just swallowing water, praise him for this, and calmly suggest that you will try again another time. Camphor. Esophagitis is painful inflammation and swelling in your esophagus. It works like a charm. Greg Ream, For bad-tasting meds, buy empty gel caps. I'm out of ideas and looking for options, if anyone has any other tips. Vitamin K1 may be given by oral, intramuscular, intravenous, or subcutaneous routes. Insert the syringe between the teeth. Trusted by the greater Denton County community and Mother Approved. 18. Then I close my mouth and swallow. Wolf, LR, Otten EJ, Spadafora MP. Coated or encapsulated pills are especially hard to swallow without fluid. Salicylate Intoxication:Significance of Measurements of Salicylate in Blood in Cases of Acute Ingestion. McCarron MM, Challoner KR, Thompson GA. Diphenoxylate-Atropine (Lomotil) Overdose in Children: An Update (Report of Eight Cases and Review of the Literature). In addition to careful evaluation, appropriate monitoring, and aggressive intervention when indicated, the emergency physician should provide educational information for all children who are evaluated for an ingestion. Authors: Daryl Emery, MD, Clinical Instructor, Wright State University School of Medicine; Jonathan I. Gut decontamination should be contemplated for an asymptomatic patient who presents promptly after suspected ingestion, especially of a sustained-release preparation. Charcoal is also recommended. Get unlimited access to our full publication and article library. For information on new subscriptions, product Garden chemicals, such as weed killer or slug pellets. Pediatrics 1991;87:694-700. 77. Garlington LN, Bailey PJ. In the literature, the minimal lethal dose is projected to be 1.25 mg/kg of diphenoxylate.71 This translates to roughly four tablets for a toddler. Symptoms of acute overdose in adults include altered mental status (agitation, confusion, drowsiness, and coma), anticholinergic effects, cardiovascular instability (hypotension, hypertension, brady and tachydysrhythmias), and neuroleptic malignant syndrome.56 Mortality, which has occurred with as little as a 200 mg ingestion in adults, results from sudden cardiac death.57, Experience with accidental acute ingestion in the pediatric population is limited. 9. It may cause symptomatology when penetrated from the skin, inhaled, or taken orally. childproofing checklist before your baby crawls, Breastfeeding: the trick to a comfy latch, Vomiting in babies: what's normal and what's not. Push your fist in and up quickly to push the object out of your throat. Rarely, hyperglycemia may contribute to an exaggerated fluid loss.107 Ultimately, the poor perfusion state is magnified by myocardial dysfunction, bradydysrhythmia, pulmonary edema, and rhabdomyolysis with renal failure.108-110, Treatment for asymptomatic children who present within one hour of ingestion include gastric lavage and activated charcoal. Dantrolene is the drug of choice for neuroleptic malignant syndrome. 54. Tribble J, Weinhouse E, Garland J. Medical conditions are sometimes to blame for pills getting stuck in your throat. Desipramine/Tricyclics. If swallowing pills becomes essential, e.g. Methanol Poisoning As a Result of Inhalation Solvent Abuse. The volume of a swallow is 0.21 ml/kg, or roughly 1 tsp for a 2 year old. The pill should disappear from the mouth. The maximal unit dose available for desipramine and imipramine is 150 mg. 66. Some young children become cooperative if you let them hold the syringe. access to 500+ CME/CE credit hours per year, and access to 24 yearly National Data Collection System. Some medications and health conditions can make it more likely that a pill will get stuck. Use the oral dosing syringe that comes with the medicine. Theophylline. Trying to work out when your child swallowed it. 104. The principle component of the latter is acetone, a product that must be consumed in large volume to create serious pediatric poisoning.18, Acetonitrile is highly toxic. If your child spits out or refuses ibuprofen, try oral acetaminophen (such as Tylenol). 88. Infants and toddlers are at greater risk of life-threatening events than older children.124 The relationship of clinical manifestations with the parameter of volume ingested is not well known.125 By and large, authors have reported clinical toxicity with measured serum theophylline levels rather than focusing on the adversity seen with a given volume of ingestion.126 Koren reported a minimum fatal dose in toddlers at 8.4 mg/kg.13 On the assumption that the threshold for toxicity approaches this value, a single 500 mg theophylline tablet may adversely effect a toddler. J Clin Psychiatr 1991;52:102-104. Acute Accidental Lindane Ingestion in Toddlers. Lying down could cause a pill to stick to the side of your throat. Activated charcoal has been reported to be ineffective,14 yet is still recommended.42 The patient should be maintained NPO and have seizure precautions taken. You can refine this. Do not squirt medicine into the back of the throat. Afterward, say: "I'm sorry we had to hold you. It's always harder to swallow pills with water. The following steps should help relieve pain and get the pill out of your throat: If the person is unconscious, call 911. If you don't have a med syringe, buy one at a pharmacy. The projected pediatric therapeutic dose of Levsin as drops for a 10 kg child is 8 drops. Charcoal and cathartics plus a four-hour period of observation are suggested for asymptomatic children. Am J Med 1982;73:564-572. Smith AG, Margolis G. Camphor Poisoning:Report of a Fatal Case. An acute overdose of a phenothiazine results in classic anticholinergic effects (flushed skin, dry mucous membranes, decreased bowel sounds, urinary retention, changes in affect), plus alterations in temperature regulation, a variety of neurologic syndromes, and cardiovascular depression. Extracorporeal Membrane Oxygenation for Hydrocarbon Aspiration. 21. A difficult pill to swallow: An investigation of the factors associated with medication swallowing difficulties. It's a tough pill to swallow. publications. Many medications come in liquid, sprinkle or chewable forms and some can be crushed or dissolved. The water helps push down the pill, and lying down relaxes your throat so the pill has room to move. Children aged 18 to 36 months seemed to be at the highest risk, and in these little bodies, just one pill can be deadly. Crushing is made easier by wetting the pill with a few drops of water. When your child can reliably swallow the Tic-Tacs or M&M's, ask him to try swallowing an actual pill. Then, take a mouthful of water. Criteria for Hospitalizing Children Who Have Ingested Products Containing Hydrocarbons. 81. trials, alternative billing arrangements or group and site discounts please call Place the thumb side of your fist above their belly button. Absorption of selenious acid is rapid from the gut. Pediatrics 1960;26:800-807. Amer J Emerg Med 1989;7:41-43. N Eng J Med 1966;275:112-113. J Anal Toxicol 1990;14:186-188. Then, have your child fill the mouth with fluid. If the event was witnessed, the caretaker may provide insight. A child 6 to 11 months typically weighs 12 to 17 pounds so they're given a dosage of 5 mL which equals 160 mg of ibuprofen as needed every 6 to 8 ho. Pills stuck that way can cause pain, anxiety, and inflammation. Gastrointestinal Dialysis with Activated Charcoal and Cathartic in the Treatment of Adolescent Intoxication. Fevers less than 102 F (39 C) are important for fighting infections. We use cookies to create a better experience. People in hospital beds may also have a tough time with pills. Am J Emerg Med 1997;15:447-492. 95. The initial maximal dose recommended for adults of methadone is 15 mg. Doses in excess of 30 mg can cause respiratory depression. She has ADD and takes medication, but we're limited to what comes in a capsule form that I can open up and mix into a spoon of yogurt or pudding. Hydrocarbons, alcohols, cleaning substances, pesticides, and gun blueing agents have been the most commonly reported pediatric fatal non-pharmaceutical ingestions.1,2,7, A diverse group of medications have been identified as particularly toxic to children younger than 2 years of age and weighing less than 10 kg. Activated charcoal is unlikely to be of use. If you help next time, we won't have to.". Why Do I Experience Shortness of Breath After Eating? Hyoscyamine, a naturally occurring tertiary amine, is one of the anticholinergic alkaloid components of the Solanaceae family of plants. Put a pill at the back of your tongue and squeeze water from a bottle into your mouth. In the pediatric population, exposure to tricyclics is largely unintentional.62 Acute ingestion in young children carries life-threatening potential. Gravity can help if you have your child in an upright position. Clin Pediatr 1985;24:687. Methanol PoisoningWhen the Stars Threw Down Their Spears. 24. irritability, possibly caused by a headache. Methanol Poisoning. Set up a reminder on your phone instead. One adult will hold the child sitting on their lap. Proud to be ranked in all 10 pediatric specialties the last five years. Buy about five (5) types, from tiny round sprinkles to large silver spheres so that you have pills of gradually increasing size. Smialek JE, Monforte JR, Aronow R, et al. For children, there is anecdotal support for treatment of excessive infantile crying (colic).82. Bhopale S, Seidel JS. The 15-30 mL packages contain from 1.8-20 mg of imidazoline. Yolken R, Konecny P, McCarty P. Acute Fluoride Intoxication. Dr. Sherman says it's easier to teach younger children to swallow pills before they have the chance to develop a fear of them. Tip: Coating the taste buds with the sweetener first may also hide the taste. Litovitz TL, Klein-Schwartz W, Dyer KS, et al. Drugs and the Treatment of Psychiatric Disorder in Goodman and GilmansThe Pharmacologic Basis of Therapeutics. Initial hypertension is promptly followed by hypotension and shock. 120. My way is to put the liquid in my mouth, tilt my head back . As little as 4 mL ingestion of oil-of-wintergreen has caused a pediatric death.105, The earliest signs and symptoms of acute methyl salicylate poisoning in children are seen within several hours.106 Hyperpnea and vomiting are typical. World J Gastroenterol. To dislodge a pill, try back blows, the Heimlich, or drinking water. The minimal lethal dose for these compounds is 15 mg/kg.13 Thus, an ingestion of 1-2 tablets could prove fatal to a toddler. 92. Pediatrics 1958;21:340-341. Usefulness of Physostigmine in Imipramine Poisoning. In severe cases, you may need a whole glass. You can also use any sweet food that doesn't require any chewing. Is there an easy way to swallow large pills? Atropine or isoproterenol is suggested for bradycardia.89, Lindane. Pediatrics 1998;84:490-494. It also has been employed with success in the treatment of rheumatoid arthritis and discoid lupus. Also, have a glass of your child's favorite drink ready to rinse the mouth. Whole Bowel Irrigation as a Decontamination Procedure After Acute Drug Overdose. Children need regular practice in order to maintain this new skill, so daily practice is important. Coma, pulmonary edema, and apnea can have a latency up to four hours post-ingestion.95, Treatment includes gastric emptying (within 1 hour of ingestion), charcoal, high-dose naloxone, and respiratory support.96,97. If you already have a subscription to this publication, please log in to view the full article. The need for an accurate assessment of quantity consumed is obviously desirable.10 If the event was unwitnessed, accuracy is compromised. The whipped cream creates a barrier so the capsule doesnt roll out and it gives him something substantial to swallow. bristoladd, My husband noticed that our daughter, who was struggling to take her meds, was able to swallow fruit-flavored Gushers whole. Media community. Liebelt and Shannon expanded the selected list by emphasizing three additional preparations in their 1993 publication (imidazoline compounds, benzocaine, diphenoxylate).14 It is our intent to revisit and update the pharmaceutical and non-pharmaceutical agents that have previously been emphasized to be highly toxic in small doses. Play with your child before giving the medicine so they see it as a good thing. J Emerg Med 1996;14:559-601. (Baby Orajel ) has produced . Available to consumers through health food stores are an array of natural remedies that are toxic. Mucosal application of benzocaine leads to rapidly measurable serum levels. It is a synthetic phenylperidine that, at high doses, has typical opioid activity. Gastric lavage carries risk of perforation. Shannon M, Lovejoy FH. Having a pill stuck in your throat is both scary and painful. Ginsburg CM, Angle CR. Activated charcoal may be of use. J Emerg Med 1998; 597-605. Our pediatric doctors and pediatric office is a resource for all your childs needs. The risk for serious toxicity after acute oral exposure to theophylline is effected by the patients age. For those toddlers with a witnessed ingestion of more than a few mouthfuls, or those who become symptomatic (heme-positive stools or spontaneous mucous membrane bleeding) treatment with vitamin K1 should be initiated. Segar WE. 57. This article provides some tips for how to avoid choking on a pill and for dislodging one that seems to be stuck. Benzocaine is metabolized by serum pseudocholinesterase to several metabolites that are methemoglobin-forming compounds. To perform back blows for the person, follow these steps: To perform the Heimlich maneuver on someone else, follow these steps: If you can see the pill blocking their throat, try to gently sweep it from their airway. Childrens Health is proud to become the first pediatric health system in the country to offer Amazon Lockers, self-service kiosks that allow you to pick up your Amazon packages when and where you need them most 24 hours a day, seven days a week. Unfortunately, the accuracy of even observant parents may be suspect.11 If directly witnessed, the volume consumed can be theoretically calculated. Ann Emerg Med 1998,31:525. Symptomatic patients require admission for at least 24 hours. J Pediatr 1993;122:514-520. Camphor is a cyclic ketone of the hydroaromatic terpene group that was obtained from the bark of the camphor tree. Siebert R, Routledge PA. Promoting Resilience in Families Experiencing Stress. It washes the pill right down." hoyarn91. The natural flow of swallowing is like a wave. Those with any symptoms other than gastrointestinal complaints should be admitted with evaluation of serum electrolytes, calcium, magnesium, and cardiac monitoring. Pediatr Ann 1995;24:23-30. 83. Put the pill on their tongue and then drink more water to swallow. Hemodynamic Effects Following Ingestion of an Imidazoline-Containing Product. 84. Shannon M. Toxicology Reviews: Physostigmine. 1. Mix the medicine with a small amount (1 to 2 teaspoons) of applesauce or pears and give it with a spoon. 63. For all fevers: Keep your child well hydrated. Heath WE. By our review, there are roughly two dozen agents that have the potential to be fatal to a toddler upon 1-2 swallows or 1-2 tablets of a marketed dose unit. Using a better technique can sometimes get rid of the child's resistance. Lomotil (Diphenoxylate and Atropine) Intoxication. Use one hand to hold the syringe. Osterhoudt KL, Wiley CC, Dudley R, et al. Adverse symptoms from Lomotil in toddlers has been reported from both therapeutic antidiarrheal trials and from accidental ingestion.69 Toxicity in the very young has been seen with ingestion of as little as two tablets.70 The senior author failed to report his personal experience of a toddler death following an accidental ingestion of two Lomotil tablets. Have your child try to swallow large gulps at a time. 1. Peer Reviewer: Leslie Wolf, MD, Associate Professor/Toxicology Coordinator, Department of Emergency Medicine, Wright State University School of Medicine, Dayton, OH. Gilman AG, et al, eds, 8th ed, New York: McGraw-Hill:383-435. Place the pill on the tongue, near the back of the throat. a condition for entering a research study or if the pill only comes in pill form and cannot be cut or crushed, ask for a referral to a therapist who has experience teaching children how to swallow medication. Clin Toxicol 1993;31:407-413. Pediatric Cyanide Intoxication and Death from an Acetonitrile Containing Cosmetic. Thorax. The alkaloid primarily acts as a blood schizonticide. Desipramine and imipramine are classic three-ringed, older "tricyclic" agents. After that, they can eat or drink again. Let your child decide how they want to take medications, which will empower them. Heart Medications If a child ingests your heart medications accidentally, it can cause his (or her) heart rate and blood pressure to drop to dangerously low levels. JAMA 1998;260:3470-3473. Seizures have been described within five minutes of ingestion.42 However, onset may be delayed for two hours post-ingestion.44 Therefore, an asymptomatic toddler, who may have ingested a small volume of camphor-containing product, should be observed in the emergency department for 3-4 hours. One such agent, thioridazine (Mellaril), like chlorpromazine, has been found to be highly toxic for pediatric patients. Rebound Severe Methemoglobinemia from Ingestion of Nitroethane Artifical-Fingernail Remover. A 2-year-old child can equally mistake a medication for an edible ingredient.6 Toddlers may observe the ritual of self medication in another family member and imitate that behavior. Nondiscrimination and Interpreters Notice, Techniques for giving liquid medicines, pills and capsules. Patients who are hypernatremic on the basis of pure sodium addition to their extracellular fluid become hypervolemic. Life-threatening symptomatology and death are in fact rare with all anticholinergic medication poisoning.83 There have, however, been a few deaths reported from atropine administration in children.84 A fatal dose of atropine was reported with1.6 mg.85. Haggerty, RJ. Phillips L, Kearns G. Pediatric Tricyclic Antidepressant Ingestions: Predictors of Morbidity. Victoria MS, Nangia BS. Eat bread. Neuroleptic Malignant Syndrome Associated with Clozapine Use. Their hands will hold the child's hands and head to keep from moving. Salt. Cyanide is eliminated by the rhodanese-mediated oxidation of endogenous thiosulfate to non-toxic thiocyanate. Hypotension is common. Acid reflux might be the reason for the change. For DSR inquiries or complaints, please reach out to Wes Vaux, Data Privacy Officer, Methanol. Methanol intoxication is possible through dermal absorption, inhalation, or ingestion.98 Inadvertent oral pediatric encounters are facilitated by unsafe household storage and lack of childproof containers. 82. As the pathway is overcome, nausea and vomiting herald toxicity. 126. Acute Methanol Poisoning. Yes! High-pitched cry, seizures, coma, and permanent neurologic sequelae occur with serum sodium concentrations reaching 160 mEq/L.120, Treatment for hypernatremic, hypervolemic patients includes augmentation of sodium excretion with diuretics as well as concomitant water administration. Vitamin K is a co-factor in the synthesis of clotting factors II, VII, IX, and X. Vitamin K facilitates the carboxylation of glutamyl residues on clotting factor precursors. Brodifacoum is one of several 4-hydroxy derivatives of coumarin. Pennyroyal oil is sold to remedy respiratory complaints, to serve as a digestive aid, and to induce menses.112, The main constituent of pennyroyal oil is pulegone. Butyrolactone. Don't leave medicines in a room so you remember to take them. The volume of a swallow by individuals of all ages is a function of body mass. The elixirs contain 0.125 mg/tsp. Mills, RW, Burke S. Gastrointestinal Bleeding in a 15-Month-Old Male: A Presentation of Munchausens Syndrome. Methyl Salicylate Poisoning: A Case Report and Discussion of Treatment by Peritoneal Dialysis. Margaret Etudo is a health writing expert with extensive experience in simplifying complex health-based information for the public on topics, like respiratory health, mental health and sexual health. We have addressed the therapeutic interventions for asymptomatic and symptomatic patients who are at risk for a morbid outcome. However, as little as 5 mL, or one swallow, in a 10 kg toddler has been reported to result in fatality.21. Your child may be able to get a battery out of a worn toy, Check that your child's toys conform to safety standard regulations. Litovitz T, Manoquerra A. Caution: Never use this technique if the medicine is not needed. If the pill doesnt go down with the first swallow, just say, keep drinking and it will probably wash down with the next gulp. All rights reserved. Young children don't understand the importance of taking a medicine. Pill-induced esophagitis. 16. 2017;72(6):576-578. doi:10.1136/thoraxjnl-2016-209540. Tenenbein M, Cohen S, Sitar DS. Another option might be to give an antibiotic in a shot. Most non-prescription medicines (OTC) are not needed. Admission for 24 hours of observation in a suspected ingestion may be appropriate. Do not swallow the water. However, respiratory depression with apnea, altered mental status, decreased peripheral perfusion, loss of gag reflex, and bradycardia may occur shortly after exposure.40 The treatment is symptomatic and supportive. Diphenoxylate may ameliorate symptoms of adult enteritis by slowing gastrointestinal motility. However, in adults, it has been reported that less than a teaspoon of pennyroyal oil can cause hepatotoxicity, and a tablespoon has proved fatal.114 There have been only a few cases of toxicity in the pediatric population, and these childrens symptoms followed exposure to several ounces of brewed tea.113.
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